Best Serrapeptase
(Note) Serracel is now called Serretia®
Serretia® by Arthur Andrew Medical far surpasses other Serrapeptase products and is our choice as the best overall Serrapeptase product. Our comparisons were based on 4 basic criteria.
1) Price
2) Strength
3) Natural quality
4) Delivery method
Finding the best priced Serrapeptase can be a challenging and confusing task. Anyone trying to find quality might choose the serrapeptase product with the highest sticker price. However, many times the item with the highest sticker price isn't always the highest quality. Our editors have calculated the price per 100,000 Serrapeptase units (SPU)'s of activity for the most popular Serrapeptase products on the market. Serretia® was the lowest priced Serrapeptase of all the major brands costing only 51 cents per 100,000 SPU's of activity. Take a look at the Best Price Serrapeptase graph below to see our results. In addition to being the best price Serrapeptase, Serretia® was surprisingly the highest strength Serrapeptase per dose as well. On average, most Serrapeptase products contribute anywhere from 20,000 to 60,000 SPU’s or Serrapeptase units per dose. Serrétia is by far the strongest Serrapeptase on the market at 250,000 SPU’s per dose. Arthur Andrew Medical uses serrapeptase in virtually all of their formulations. Serrapeptase is one of the most medically universal enzymes available. Clinical studies show the enzyme reduces arterial plaque, inflammation, fibrin and blood clots. Serrapeptase treats sinus infections and is one of the best natural decongestants. Please find our Highest Strength Serrapeptase graph below to see our results.
Arthur Andrew Medical® blends several thousand Kilos of serrapeptase per year allowing them to manufacture the enzymes significantly cheaper. Arthur Andrew normally stocks serrapeptase in several activities and is available for private label manufacturing. All raw materials are naturally BPA and phthalate (plastic) free, and come in Acid Armor capsules for 100% natural acid protection. Enteric coated powders and capsules are available for an additional cost.
Best Price Serrapeptase
(Note) Serracel is now called Serretia®
Price per 100,000 SPU's has been calculated based on the Manufacturer's listed MSRP.
This graph indicates the cost of Serrapeptase per 100,000 Serrapeptase Units. At retail, the least expensive brand of Serrapeptase is Serrétia, manufactured by Arthur Andrew Medical with the most expensive brand being Solaray.
The graph above demonstrates the cost per 100,000 SPU's of Serrapeptase activity.
Arthur Andrew Medical brand of Serrapeptase brand name Serrétia, demonstrates the highest cost per activity savings over the most popular brands. Serrétia is extremely impressive as it was not only the strongest Serrapeptase, but also the cheapest in terms of cost. Out of all of the major brands compared, Serrétia was the only brand that didn't use HPMCP (Hydroxypropyl Methylcellulose Phthalate) in the manufacturing process.
See graph featured at right
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Highest Strength Serrapeptase (per dose)
(Note) Serracel is now called Serretia® rated at over 250,000 SPU's
Choosing a serrapeptase enzyme supplement is not always easy. Although most supplements claim they provide numerous serrapeptase benefits, such as reducing inflammation, preventing blood clots and dissolving scar tissue, not all of them perform exactly the same. Therefore, whether you are looking to use serrapeptase for prevention, treatment or pain relief, it is extremely important to choose the best serrapeptase enzyme brand. If you expect to simply pay more to get a higher quality serrapeptase, you may be disappointed. In certain cases the retail cost of a product has to do with the relationship of the vendor to the manufacturer. If the vendor is buying direct from the manufacturer the price is usually more affordable than if that vendor is buying from a middleman.
Delivery Method
Instead of using any type of enteric-coated serrapeptase, the serrapeptase supplement Serretia® uses a different technology known as Acid Armor®. Acid Armor capsules are made of an extra-thick layer of cellulose (the main component of veggie caps) with a micro-threaded locking mechanism that seats the two sides of the capsules together tightly, limiting premature repture of the capsules contents. Acid Armor capsules have also been designed to delay the release of the capsule's contents for up to an hour. When a product like Serrétia is taken on an empty stomach, the capsule enters and leaves the stomach in 30 minutes or less. This means that the Acid Armor provides more than enough time for the serrapeptase enzyme to get through the stomach and into the more "enzyme friendly" environment of the intestines.
In addition, serrapeptase capsules themselves do not cause the stomach to start producing acid when they are taken on an empty stomach. Acid production normally occurs when the stomach fills up with food and its lining is stretched. Therefore any tests that supposedly "prove" the necessity of enteric-coated serrapeptase by exposing enzymes to extremely acidic environments for several hours do not accurately replicate actual, real-life conditions in an empty stomach!
Acid Armor vs Enteric Coating
For years there has been a belief circulating that serrapeptase and other systemic enzymes will be destroyed by acid in the stomach if they are not protected. According to the companies that circulate that belief, the only way to shield serrapeptase from destruction is to use enteric coating. Enteric coatings are made from plastics and other chemicals. The most common methods are enteric coated capsules and enteric coated raw enzyme powders. This is supposed to protect the enzymes from the stomach acids and release them in the intestines. However, there are currently no clinical studies that demostrate this effect. Arthur Andrew Medical designed Acid Armor capsules to deliver enzymes precisely below the stomach, rather than mixing enteric coated enzymes with acid in the stomach and hoping they survive.
While it is true that certain enzymes, usually those derived from animals, become less active in very acidic environments, our testing has revealed that enteric coating can prevent proper absorption and can limit bioavailability. A series of third-party tests, products containing enteric-coated serrapeptase powder lost more activity than supplements using non-enteric-coated serrapeptase powder. Raw food diets contain high levels of natural enzymes, not enteric coated enzymes. These enzymes have evolved to survive a wide range of different pH levels. Therefore, enteric coatings are only important (in theory) for animal-based enzymes that are naturally released in the digestive tract after the stomach. Animal pancreatic enzymes were designed by nature to survive a limited pH range.
| Brand | Serrapeptase Activity (per dose) | Coating2 |
| Serretia® | 250,000 SPU | Acid Armor® capsule |
| Doctor's Best Serrapeptase | 80,000 IU | Enteric-coated capsules |
| Serra Enzyme™ | 160,000 IU | Enteric-coated capsules |
| Source Naturals Serrapeptase | 120,000 SPU | Enteric-coated capsules |
| Solaray Serrapeptase | 40,000 IU | Enteric-coated capsules |
| Vitamin Shoppe Serrapeptase | 80,000 SPU | Enteric-coated capsules |
| Serra Rx Serrapeptase | 160,000 SPU | Enteric-coated powder Serrapeptase |